Radioactive Iodine Therapy (RAI)
What is the role of RAIA in the treatment of high-risk thyroid cancers?
RAI treatment is controversial in papillary, follicular and Hürtle cell cancers of the thyroid.
Current guidelines recommend using RAIA therapy in high-risk tumors.
High-risk tumors include:
Tumor extending beyond the thyroid tissue,
Tumor tissue was left behind during surgery and
It has metastasized to the body.
What is the role of RAIA in the treatment of intermediate-risk thyroid cancers?
In medium-risk tumors, the decision whether to apply RAI or not is made on a case-by-case basis.
Intermediate risk tumors include:
Microscopic spread of the tumor outside the thyroid tissue after surgery,
Presence of metastatic foci sensitive to RAIA in the neck,
Some aggressive tumor types,
Tumors involving blood vessels and
Tumors that have spread to the lymph nodes in the neck.
What is the role of RAIA in the treatment of low-risk thyroid cancers?
In low-risk tumors, if no tissue is left behind during surgery, RAIA treatment is not required.
Low-risk tumors include:
Tumors in which all of the thyroid tissue is removed,
Situations where the tumor does not extend beyond the thyroid tissue,
Some tumor types have a better prognosis,
Tumors that have not metastasized to the body.